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there have been continuing rapid advances in many of the technologies used to obtain the raw data of bioinformatics, such as DNA sequencing, as well as enormous increases in widely available computing power, and discoveries have continued apace. There has also been a global pandemic, combating which has been greatly assisted by bioinformatics, and which vastly boosted data acquisition. These developments alone warranted thorough revision of the material in the book. The opportunity has also been taken to somewhat rearrange the chapter topics, although admittedly in such a multidimensional subject as bioinformatics there is probably no ideal arrangement.
There has been a significant increase in the space accorded to regulatory networks and their analysis, which is now in better balance with the nucleic acid sequencing aspects, which are usually perceived as the traditional subject matter of bioinformatics; the transmission of information within the networks, and their architecture, deserve comparable prominence. We are becoming accustomed to the idea that life is organized heterarchically and that our DNA is just one of many features contributing to a living organism, which must survive a lifetime in a changing environment, during which its DNA sequence is not changing.
author/Jeremy Ramsden
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